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Structural Biology and AI: From an Integrated Engine for Drug Discovery

Viva Answers | Episode 3

Structural Biology and AI: From an Integrated Engine for Drug Discovery

 

 

In Episode 3 of Viva Answers, Yichen (Jerry) Zhang, Senior Director of Biology at Viva Biotech, shares how we select the right structural biology approach for each target, deliver high-quality structural data at scale (~16,000 crystal structures annually), and connect structural insights, AIDD/CADD, and experimental validation in a closed-loop workflow to accelerate lead optimization.

 

Key Topics

 

1. X-ray crystallography or Cryo-EM — which one should I choose for my target?

2. Viva Biotech determines approximately 16,000 crystal structures every year. How do you achieve that scale, and what about data quality and resolution?

3. How does AI-driven computation, including AIDD/CADD, work together with structural biology to accelerate drug discovery?

Introduction
Yichen (Jerry) Zhang
Senior Director of Biology, Viva Biotech
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