(1) Generation of stable cell lines
(2) Establishment of cell based drug screening model
· Reporter gene assay, calcium mobilization and cAMP detection could be used for GPCR; Viva Biotech has 57 internally established GPCR cell lines that can provide services.
· Reporter gene assay based on nuclear receptor.
· Detection based on FACS, including cell cycle, apoptosis, etc.
· Detection of phosphorylated protein level and cytokines based on a signal pathway,including the methods such as ELISA, WB and HTRF.
· Viva Biotech has more than 180 types of cancer cells available for cell proliferation assay with 96-well/384-well format.
Cell based case：
(1) Target type:
· Protein kinase
· Epigenetic targets/p>
· Other enzymes (phosphodiesterase, ATP kinase, and protease)
· Nucleotide receptor
· Immune tumor targets
(2) Detection type：
· Biochemical detection: HTRF, ADP/AMP/Kinase Glo, Ulight and Zlyte etc.
· Target binding detection: FP, Lanthascreen, Alpha, TR-FRET,ELISA, and Probereplacement etc.
“Bioassay”, please contact our team.