Breaking the Expression Bottlenecks of Challenging Targets in Recombinant Protein Production

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Viva Answers | Episode 1

Breaking the Expression Bottlenecks of Challenging Targets in Recombinant Protein Production

Producing high-quality recombinant proteins for challenging targets is often one of the first major hurdles in drug discovery.

In this episode, Dr. Jian Shen, Vice President of Protein and Structural Biology at Viva Biotech, shares practical strategies for addressing common protein expression challenges, including expression system selection, the production and stabilization of difficult membrane proteins, and protein production at different scales.

Key Topics

1. How do I determine the most appropriate expression system for my target protein?

2. What strategies can be used to express and stabilize difficult-to-express membrane proteins such as GPCRs?

3. What protein production and scale-up capabilities does Viva Biotech offer to support projects from early-stage screening through in vivo studies?

Introduction

Jian Shen

Vice President of Protein & Structural Biology, Viva BIotech

Content you may be interested

Protein Expression and Purification

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