MicroED is a powerful technique used to resolve the high-resolution structure of small molecule compounds. Microcrystals are too small to be administered by X-ray crystallography but their diffraction patterns can be collected with an electron beam. The diffraction dataset can be processed by conventional crystallographic programs for a rapid atomic resolution (usually better than 1 Å) structure determination. Large efforts are usually required to make microcrystals grow bigger for the X-ray crystallography method. With less sample requirement and less time consumption, microED serves as an ideal approach to determine the structure and crystal form of chemical compounds.
“Structural Biology Services”, please contact our team.