Viva biotech is dedicated to providing integrated drug discovery services, from hit to preclinical drug candidate’s research.
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Outline Services:
6 Drug Discovery Enabling Programs:
1. Gene-to-structure (g2s)
2. Gene-to-protein (g2p)
3. Structure-based drug design / fragment based lead generation (SBDD/FBDD(FBLG)) (X-ray, Mass, NMR, SPR, Assay and Medichem)
4. Target validation, target ID, biomarker identification
5. Antibody therapeutic discovery using phage display
6. Hit-to-lead and lead optimization
>10 Technique Expertise:
1. Protein expression, purification and crystallography
Protein expression profiling
Protein-protein complex
Membrane protein g2p and g2s
Co-crystallization
2. Selective methyl isotope labeling NMR protein production
3. Mammalian over-expression systems
4. Stable cell line generation
Lentivirus mediated cell line generation (gene over-expression/knockdown)
Flp-in stable cell line generation
5. Antibody disocery using phage-display technology
6. SiRNA and ShRNA mediated gene knockdown
7. Target ID using click chemistry
8. Mass spectrometry based ligand binding studies
9. Radio-isotope labeled DMPK studies
10. Cell-based GPCR assay platform
11. Pain animal models (CCI, SNL, CFA, and etc)
For other services you might be interested in, please inquire online.